Myriad Genetics Licenses Cancer Drug Technology to Salmedix
SALT LAKE CITY, May 24 /PRNewswire-FirstCall/ -- Myriad Genetics, Inc.
(Nasdaq: MYGN), announced today that it has exclusively licensed its
technology for using the single R-enantiomer of etodolac to Salmedix, Inc. for
the development of cancer therapeutics. Myriad received a $2.5 million upfront
payment from Salmedix and will receive milestone payments based on the
achievement of developmental and commercialization objectives as well as
royalties on net sales.
Myriad's technology is covered by several issued and pending patents in
the United States, Europe and Japan. This intellectual property will provide
additional proprietary protection to Salmedix around its clinical drug
candidate SDX-101 and other potential analogs.
"We are pleased that Myriad's intellectual property will be used in a non-
competitive cancer drug development program which has the potential for
further returns to our shareholders in the future," said Peter Meldrum,
President and Chief Executive Officer of Myriad Genetics, Inc.
SDX-101 is R-etodolac, a single enantiomer of etodolac. Etodolac is a
mixture of two mirror image forms, called the R and S isomers. SDX-101, the
R isomer of etodolac, preferentially induces apoptosis in malignant
lymphocytes by a novel mechanism and is substantially devoid of anti-
inflammatory activity. In September 2004, Salmedix initiated a Phase 2
clinical trial in which 80 patients with chronic lymphocytic leukemia will
receive a standard chemotherapy regimen alone or in combination with SDX-101
for multiple cycles.
On May 12, 2005, Cephalon, Inc. (Nasdaq: CEPH) announced that it had
signed a definitive merger agreement under which it will acquire all of the
outstanding capital stock of Salmedix, Inc.
Myriad Genetics, Inc. is a biopharmaceutical company focused on the
development of novel healthcare products. The Company develops and markets
predictive medicine products, and is developing and intends to market
therapeutic products. Myriad's news and other information are available on
the Company's Web site at www.myriad.com.
This press release contains "forward-looking statements" within the
meaning of the Private Securities Litigation Reform Act of 1995. These
forward looking statements are based on management's current expectation and
are subject to certain risks and uncertainties that could cause actual results
to differ materially from those set forth or implied by forward-looking
statements. These include, but are not limited to, uncertainties as to the
extent of future government regulation of Myriad Genetics' business;
uncertainties as to whether Myriad Genetics and its collaborators will be
successful in developing, and obtaining regulatory approval for, and
commercial acceptance of, therapeutic compounds; the risk that markets will
not exist for therapeutic compounds that Myriad Genetics develops or if such
markets exist, that Myriad Genetics will not be able to sell compounds, which
it develops, at acceptable prices; and the risk that the Company will not be
able to sustain revenue growth for its predictive medicine business and
products. These and other risks are identified in the Company's filings with
the Securities and Exchange Commission, including the Company's Annual Report
on Form 10-K for the fiscal year ended June 30, 2004. All information in this
press release is as of May 24, 2005, and Myriad undertakes no duty to update
this information unless required by law.
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